Body

More evidence that spicing up broccoli boosts its cancer-fighting power

URBANA – Teaming fresh broccoli with a spicy food that contains the enzyme myrosinase significantly enhances each food's individual cancer-fighting power and ensures that absorption takes place in the upper part of the digestive system where you'll get the maximum health benefit, suggests a new University of Illinois study.

"To get this effect, spice up your broccoli with broccoli sprouts, mustard, horseradish, or wasabi. The spicier, the better; that means it's being effective," said Elizabeth Jeffery, a U of I professor of nutrition.

Cardiotrophin 1 shows promising results for treatment of obesity and metabolic syndrome

Scientists from the Center for Applied Medical Research (CIMA) of the University of Navarra (Spain) have discovered that cardiotrophin 1, a protein synthesized by muscle cells and adipose tissue, has a marked effect on fat and glucose metabolism. "These new findings add to those we already know on this compound such the anti-ischemic and cytoprotective effects showed in acute liver damage and solid organ transplants gives CT-1 great possibilities to be developed in various serious conditions", commented Pablo Ortiz, CEO of Digna Biotech.

Small molecule receptor detects lipid's telltale sign of cell death

CHESTNUT HILL, MA (9/13/2011) – Researchers from Boston College have developed a new class of small molecule receptors capable of detecting a lipid molecule that reveals the telltale signs of cellular death, particularly cancer cells targeted by anti-cancer drugs, the team reports in the current electronic edition of the Journal of the American Chemical Society.

Freeze and desist: Disabling the cardiac cells that can cause arrhythmia

Chicago – Many patients are responding to a new, minimally invasive way of treating irregular heartbeats by freezing out the bad cells. Atrial fibrillation (A-Fib) is one such heart rhythm disorder, and it's the most common arrhythmia affecting Americans. However, new research shows that 70 percent of patients with the disorder who were treated with cryoballoon ablation, the freezing technique, are free of any heart rhythm irregularities one year out from having the procedure.

Day/night cycle even more important to life than previously suspected

Researchers at USC were surprised recently to discover just how much the rising and setting of the sun drives life on Earth – even in unexpected places.

Their findings, which appear this month in the Proceedings of the National Academy of Sciences, "speak volumes to the evolution of life on Earth," according to USC scientist Andrew Y. Gracey.

"Everything is tied to the rotation of the planet," he said.

Fathers wired to provide offspring care

EVANSTON, Ill. --- A new Northwestern University study provides compelling evidence that human males are biologically wired to care for their offspring, conclusively showing for the first time that fatherhood lowers a man's testosterone levels.

Novel drug combination offers therapeutic promise for hard-to-treat cancers

Boston, MA - Researchers at Brigham and Women's Hospital (BWH) have identified a new combination of targeted therapies that, together, may treat two aggressive tumor types that until now have not had effective treatments. These findings are published in Cancer Cell on September 13, 2011.

First proof in patients of an improved 'magic bullet' for cancer detection and radio-therapy

LA JOLLA, CA - Oncologists have long sought a powerful "magic bullet" that can find tumors wherever they hide in the body so that they can be imaged and then destroyed. Until recently scientists accepted the notion that such an agent, an agonist, needed to enter and accumulate in the cancerous cells to act. An international research team has now shown in cancer patients that an investigational agent that sticks onto the surface of tumor cells without triggering internalization, an antagonist, may be safer and even more effective than agonists.

Clemson University peach specialist unveils CaroTiger, something to roar about

CLEMSON, S.C. — Celebrating the end to a successful peach season, Clemson University peach specialist Desmond Layne announced the naming of a new peach cultivar — CaroTiger. The fourth in the "Caro" — for South Carolina — series, this late-season peach will be available to growers in January 2013.

3 in 1: team finds the gene responsible for three forms of childhood neurodegenerative diseases

Making 1 into 2 -- first German genome comprehensively resolved at its molecular level

X-ray protein probe leads to potential anticancer tactic

Researchers at Emory University School of Medicine have identified a new type of potential anticancer drug. The compound, named FOBISIN, targets 14-3-3 proteins, important for the runaway growth of cancer cells.

The researchers were using X-rays to see how FOBISIN fits into the clamp-shaped 14-3-3 protein structure. Unexpectedly, the X-rays induced the compound to be permanently bonded to the protein. The finding suggests that compounds like FOBISIN can be used in combination with radiation to trigger potent anticancer activity.

Researchers discover blood proteins associated with early development of lung cancer

SEATTLE – A research team led by Fred Hutchinson Cancer Research Center has discovered proteins in the blood that are associated with early lung cancer development in mice and humans. The advance brings the reality of a blood test for the early detection and diagnosis of lung cancer a step closer.

The findings, by a team led by Samir Hanash, M.D., Ph.D., head of the Hutchinson Center's Molecular Diagnostics Program and member of its Public Health Sciences Division, are published online Sept. 12 ahead of the Sept. 13 print issue of Cancer Cell.

Lung cancer signatures in blood samples may aid in early detection

Lung cancer is one of the most common and deadly types of cancer. Mouse models of lung cancer recapitulate many features of the human disease and have provided new insight about cancer development, progression and treatment. Now, a new study published by Cell Press in the September 13th issue of the journal Cancer Cell identifies protein signatures in mouse blood samples that reflect lung cancer biology in humans.

Fish oil reduces effectiveness of chemotherapy

Researchers at University Medical Center Utrecht, the Netherlands, have discovered a substance that has an adverse effect on nearly all types of chemotherapy - making cancer cells insensitive to the treatment. Chemotherapy often loses effectiveness over time. It is often unclear how or why this happens.