Chemotherapy is one of the primary treatments for cancer. However, one of the most disturbing findings of recent studies of cancer survivors is the apparent prevalence of chemotherapy-associated adverse neurological effects, including vascular complications, seizures, mood disorders, cognitive dysfunctions, and peripheral neuropathies. In addition, chemotherapy triggers changes in ion channels on dorsal root ganglia and dorsal horn neurons that generate secondary changes resulting in neuropathic pains.
Brain
A UCLA-led study of HIV-positive women who were sexually abused as children has found that the more severe their past trauma, the greater their improvement in an intervention program designed to ease their psychological suffering.
The study, conducted by researchers at UCLA's Collaborative Center for Culture, Trauma and Mental Health Disparities, suggests that such interventions should be tailored to individuals' experience and that a "one size fits all" approach may not be enough to successfully reduce women's depression, post-traumatic stress and anxiety symptoms.
Rodents are frequently used as animal models for ischemic stroke studies induced by middle cerebral artery occlusion. However, their anatomic structure is significantly different from humans. Thus, recent studies have focused on developing stroke models in large animals with similar anatomic structure as the human brain. The swine have several properties resembling the human brain, including brain volume and weight, quantity of cortical gyri and the percentage of white matter to gray matter.
Recent findings suggest that Toll-like receptor 4 expressed in the central nervous system, especially in glial cells, plays a vital role in neuroinflammation and neurodegenerative conditions. Traditional theory suggests that neurons are injured by inflammatory factors released from glial cells, and that neurons are the victims of neuroinflammation. However, it has recently been suggested that Toll-like receptor 4 is expressed by cerebral cortical neurons.
Exceptional spatial ability at age 13 predicts creative and scholarly achievements over 30 years later, according to results from a new longitudinal study published in Psychological Science, a journal of the Association for Psychological Science.
BOSTON – When Georgetown University neurologist R. Scott Turner, MD, PhD, began enrolling people with mild to moderate Alzheimer's disease into a nationwide study last year, he expected to find only a handful of participants with undiagnosed glucose intolerance, as all the patients were already under a doctor's care and those with known diabetes were excluded. But Turner says he was "shocked" by how many study participants were found to have pre-diabetes — a finding that is triggering important questions.
CHICAGO, IL – Athletes who didn't get enough sleep the night before undergoing baseline concussion testing didn't perform as well as expected, say researchers presenting their work today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in Chicago, IL.
AMHERST, Mass. – A new study by psychology researchers suggests that whether parents are gay, lesbian or straight, how well they work together as a couple and support each other in parenting is linked to fewer behavior problems among their adopted children and is more important than their sexual orientation.
A study by researchers at Neuroscience Research Australia (NeuRA) is the first to demonstrate that patients with frontotemporal dementia (FTD) lose the emotional content/colour of their memories. These findings explain why FTD patients may not vividly remember an emotionally charged event like a wedding or funeral.
The research team discovered that a region of the brain, called the orbitofrontal cortex, plays a key role in linking emotion and memories.
Published today in the journal Science, Professor Frank Caruso from the Department of Chemical and Biomolecular Engineering at The University of Melbourne and his team have developed a new strategy to coat microscopic materials, leading to a new-generation particle system with engineered properties.
This is expected to underpin advances in the delivery of therapeutics in the areas of cancer, vaccines, cardiovascular disease and neural health.
Electroencephalography is a test to measure the electrical activity of the brain generated by scalp surface after being picked up by metal electrodes and conductive media. Proper classification of electroencephalography data is the main task in electroencephalography based brain computer interface. Brain-computer interface is a communication system that connects the brain with computer (or other devices) but is not dependent on the normal output of the brain (i.e., peripheral nerve and muscle).
Scientists have created a virtual model of the brain that daydreams like humans do.
Researchers created the computer model based on the dynamics of brain cells and the many connections those cells make with their neighbors and with cells in other brain regions. They hope the model will help them understand why certain portions of the brain work together when a person daydreams or is mentally idle. This, in turn, may one day help doctors better diagnose and treat brain injuries.
Young men who are gang members suffer unprecedented levels of psychiatric illness, placing a heavy burden on mental health services, according to new research led by Queen Mary, University of London.
The National Institute for Health Research (NIHR) and Maurice & Jacqueline Bennett Charitable Trust funded study surveyed 4,664 men aged 18 to 34 in Britain. The survey covered measures of psychiatric illness, violence and gang membership. It is the first time research has looked into whether gang violence is associated with psychiatric illness, other than substance misuse.
There are clear risk factors for postpartum psychosis that all women should be asked about antenatally to ensure early recognition and prompt treatment of the condition, says a new review published today (12 July) in The Obstetrician & Gynaecologist (TOG).
Postpartum psychosis is a severe mental illness with a dramatic onset shortly after childbirth, affecting approximately 1-2 in 1000 deliveries. However, the review notes that the true incidence may be higher.
This news release is available in Japanese.
A new study reveals that the representation of complex features in the brain may begin earlier—and play out in a more cumulative manner—than previously thought.