UCLA and biotech company develop first blood test to measure key hormone that regulates iron

Posted By News On August 8, 2008 - 7:10pm

FINDINGS:

UCLA and Intrinsic LifeSciences, a San Diego biotech company, developed the first method to measure the hormone, hepcidin, which regulates the absorption of dietary iron and its distribution in the body. This new blood test will help clinicians manage chronic conditions affecting millions of people worldwide such as anemias and iron overload diseases.

IMPACT:

The new test will measure the amount of hepcidin in the blood. When levels of the hormone are too high, the availability of iron is blocked, leading to conditions like anemia of chronic disease. When levels are low, too much iron is absorbed from the diet and released into the blood, leading to iron toxicity and conditions like hemochromatosis or iron overload disease. The current tests do not measure hepcidin but instead measure some of its direct and indirect effects on iron and the iron-binding proteins transferrin and ferritin. The new blood test will directly measure hepcidin, offering more information to clinicians to help diagnose conditions and monitor the levels of this important hormone in their patients -- leading to more efficient management of these chronic diseases.

Post new comment

The content of this field is kept private and will not be shown publicly.
  • Allowed HTML tags: <a> <em> <img> <strong> <object> <cite><p><br><i><b><center><ul><li><div><html5:figure><html5:figcaption>
  • Lines and paragraphs break automatically.

More information about formatting options

CAPTCHA
Sorry, we know you're not a spambot, but they're out there