Previously, scientists had been able to create and determine the structure of 'cages' formed by parts of the protein coats that encase other types of vesicles, but this study, published online today in Science, was the first to obtain high-resolution images of complete vesicles, budded from a membrane.
Depicting each copy of COPI as a triangle, the different arrangements of these building blocks become easier to spot.
Posted On: May 25, 2012 - 9:32pm
COLUMBIA, Mo. — For 5,000 years, the Chinese have used a system of medicine based on the flow and balance of positive and negative energies in the body. In this system, the appearance of the tongue is one of the measures used to classify the overall physical status of the body, or zheng. Now, University of Missouri researchers have developed computer software that combines the ancient practices and modern medicine by providing an automated system for analyzing images of the tongue.
Posted On: May 25, 2012 - 9:31pm
Recent recommendations from the U.S. Preventive Services Task Force (USPSTF) advising elimination of routine prostate-specific antigen (PSA) screening for prostate cancer in healthy men are likely to encounter serious pushback from primary care physicians, according to results of a survey by Johns Hopkins investigators.
Posted On: May 25, 2012 - 9:00pm
(SACRAMENTO, Calif.) — UC Davis researchers have found that workers' compensation insurance is not used nearly as much as it should be to cover the nation's multi-billion dollar price tag for workplace illnesses and injuries. Instead, almost 80 percent of these costs are paid by employer-provided health insurance, Medicare, Medicaid, Social Security and other disability funds, employees and other payers.
Posted On: May 25, 2012 - 7:00pm
HOUSTON –HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.
This chain of events, the scientists found, promotes Herceptin resistance in breast cancer and activation of glucose metabolism (glycolysis), which cancer cells primarily rely on to fuel their growth and survive.
Posted On: May 25, 2012 - 3:30pm
Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute to cancer.