Exon-skipping drug prevents muscle wasting, maintains muscle function in dystrophin deficient mice

This is a supplementary video to the Molecular Therapy publication "Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping" showing visual evidence of mouse with pronounced curving of the spine and dramatically reduced mobility as a result of deficiency of both dystrophin and utrophin proteins.

(Photo Credit: University of Oxford)

This is a supplementary video to the Molecular Therapy publication "Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping"illustrating the impact of PPMO treatment on dKO mouse.

(Photo Credit: University of Oxford)

Source: RATHBUN COMMUNICATIONS, INC.