Brain

Investigators at St. Jude Children's Research Hospital have mapped out many of the dynamic genetic and biochemical changes that make up a cell's response to a shortage of a molecule called Coenzyme A (CoA), a key player in metabolism. The results provide the most detailed look ever obtained of the complex metabolic changes in a cell triggered by a potentially fatal stress.

Modern man"s earliest known close ancestor was significantly more apelike than previously believed, a New York University College of Dentistry professor has found.

Fresh evidence that suggests monkeys can learn skills from each other, in the same manner as humans, has been uncovered by a University of Cambridge researcher.

Dr Antonio Moura, a Brazilian researcher from the Department of Biological Anthropology, has discovered signs that Capuchin monkeys in Brazil bang stones as a signalling device to ward off potential predators.

For parents, 8 million cases of acute middle ear infections every year add up to a lot of sleepless nights and trips to the pediatrician. But new research from a collaboration between Rockefeller University and St. Jude Children’s Hospital could change all that.

Researchers at the Johns Hopkins School of Medicine and their colleagues have found that mice simply expressing a human light receptor in addition to their own can acquire new color vision, a sign that the brain can adapt far more rapidly to new sensory information than anticipated.

This work, appearing March 23 in Science, also suggests that when the first ancestral primate inherited a new type of photoreceptor more than 40 million years ago, it probably experienced immediate color enhancement, which may have allowed this trait to spread quickly.

Playground roughhousing has long been a tradition of children and adolescents, much to the chagrin of several generations of parents who worry that their child will be hurt or worse, become accustom to violence and aggression. But animal research may paint a different portrait of rough and tumble play; one that suggests that social and emotional development may rely heavily on such peer interaction.

Within the mind of every smoker trying to quit rages a battle between the higher-order functions of the brain wanting to break the habit and the lower-order functions screaming for another cigarette, say researchers at Duke University Medical Center. More often than not, that cigarette gets lit.

Disrupt the gene that regulates the biological clocks in mice and they become manic, exhibiting behaviors similar to humans with bipolar disorder, UT Southwestern Medical Center researchers have found.

Scientists' inability to follow the whereabouts of cells injected into the human body has long been a major drawback in developing effective medical therapies. Now, researchers at Johns Hopkins have developed a promising new technique for noninvasively tracking where living cells go after they are put into the body. The new technique, which uses genetically encoded cells producing a natural contrast that can be viewed using magnetic resonance imaging (MRI), appears much more effective than present methods used to detect injected biomaterials.

Psychiatric researchers at The Zucker Hillside Hospital campus of The Feinstein Institute for Medical Research have uncovered evidence of a new gene that appears to increase the risk of developing schizophrenia, a disorder characterized by distorted thinking, hallucinations and a reduced ability to feel normal emotions..