Body

A natural compound from magnolia cones blocks a pathway for cancer growth that was previously considered "undruggable," researchers have found.

A laboratory led by Jack Arbiser, MD, PhD, at Emory University School of Medicine, has been studying the compound honokiol, found in Japanese and Chinese herbal medicines, since discovering its ability to inhibit tumor growth in mice in 2003.

Common genetic variations affecting nicotine receptors in the nervous system can significantly increase the chance that European Americans who begin smoking by age 17 will struggle with life-long nicotine addiction. Published July 11 in the open-access journal PLoS Genetics, this research – led by scientists at the University of Utah together with colleagues from the University of Wisconsin – highlights the importance of preventing early exposure to tobacco through public health policies.

Salt Lake City – Common genetic variations affecting nicotine receptors in the nervous system can significantly increase the chance that European Americans who begin smoking by age 17 will struggle with lifelong nicotine addiction, according to researchers at the University of Utah and their colleagues at University of Wisconsin-Madison. The study, published in the July 11, 2008 issue of PLoS Genetics, highlights the importance of public health efforts to reduce the number of youth who begin smoking.

A study published July 11th in the open-access journal PLoS Pathogens suggests that herpesviruses use multiple strategies to manipulate important components of the host cell nuclear environment during infection. The study, conducted by researchers at the University of Toronto in collaboration with Affinium Pharmaceuticals Inc., provides novel insights into the potential functions of over 120 previously uncharacterized viral proteins.

Malaria is one of the most devastating diseases afflicting humanity. It infects and debilitates about 600 million people and kills up to three million people every year, mainly in the wet tropical regions of the world. Children and pregnant women are at particularly high risk.

(Santa Barbara, Calif.) - It took a decade of painstaking study, the cooperation of hundreds of researchers, and a database of more than 200,000 fossil records, but John Alroy thinks he's disproved much of the conventional wisdom about the diversity of marine fossils and extinction rates.

The nation's fourth and eighth graders scored higher in reading and mathematics than they did during their last national assessment, according to the federal government's latest annual statistical report on the well-being of the nation's children. Not all the report's findings were positive; there also were increases in the adolescent birth rate and the proportion of infants born at low birthweight.

OAK BROOK, Ill. ¡§C JULY 11, 2008 -- A study presented at Digestive Disease Week® 2008 examined the American College of Radiology's (ACR) CT colonography guidelines recommending that polyps ≤ 5mm in size not be reported on CT colonography by applying them to an endoscopic database that collected information about polyps that had been removed and processed. The guidelines also recommend that patients with one or two polyps 6 to 9 mm in size and no larger polyps can have repeat CT colonography in three years rather than prompt polypectomy.

Sounding the chest with a cold stethoscope is probably one of the most commonly used diagnostics in the medical room after peering down the back of the throat while the patient says, "Aaaah". But, research published in the inaugural issue of the International Journal of Medical Engineering and Informatics looks set to add an information-age approach to diagnosing heart problems. The technique could circumvent the problem of the failing stethoscope skills of medical graduates and reduce errors of judgment

(Boston)-Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) found that sexual behavior counseling during drug addiction treatment should be considered an important component among Russian substance-dependent individuals, in order to decrease risky sexual behavior in the HIV at-risk population. This study appears in the journal Addiction.