Body

As the opioid crisis escalates, the science behind addiction remains poorly understood. To address this need, researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self-administer doses of hydrocodone, an opioid commonly prescribed to people for pain. After one-week, the fish had increased their drug-seeking behavior, even when doing so required them to put themselves in risky conditions. Further, 48-hours after the last exposure, conditioned fish showed signs of anxiety, a hallmark of withdrawal.

Key Takeaways:

A common type of flame retardant was associated with reduced likelihood of clinical pregnancy and live birth following IVF.

Couples undergoing IVF may want to opt for products that are flame-retardant free.

ROCHESTER, Minn. - A new study has found that a condition that threatens the lives of some pregnant women and the fetus may continue to put the mother at risk later in life.

Mayo Clinic researchers found that women with a history of pre-eclampsia are more likely to face atherosclerosis - hardening and narrowing of the arteries -- decades after their pregnancy. The findings are published in the September issue of Mayo Clinic Proceedings.

New Haven, Conn.-- Yale experts and their partners in a national research consortium have identified several genes and gene clusters associated with the immune response to flu vaccination. The findings point to the prospect of using genetic profiles to predict individual responses to the flu vaccine.

The research was published August 25 in Science Immunology.

Cancer treatments, including chemotherapy, have helped many of those who have been diagnosed with the disease to go on to live healthy lives.

Nevertheless, chemotherapy takes a toll on the body. During treatment, chemotherapy attacks all of the body's cells, not just cancer cells. The result destroys healthy cells, causing many patients to suffer major side effects during and after treatment.

And because current treatments aren't specifically targeted to cancer cells, only 0.01 percent of chemotherapy drugs actually reach the tumor and its diseased cells.

In the journal Current Aging Science, a research team has reviewed modifiable risk factors for Alzheimer's and Parkinson's diseases. The reviewers focus on the possible role of neuroinflammation (inflammation of the nervous tissue) in neurodegenerative disease mechanisms. Alzheimer's disease and Parkinson's disease are among the most common causes of dementia, and increasingly contribute to morbidity and mortality worldwide.

Orlando, Fla., Aug. 25, 2017 - Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) in Lake Nona, Florida have shown that enhanced natriuretic peptide (NP) signaling in adipose tissue protects against obesity and insulin resistance. The findings suggest that boosting levels of NPs in adipose tissue may be an important avenue to explore for combating metabolic disease. The study was published in Science Signaling.

Whenever an organism is damaged, the cells surrounding the wound receive signals to proliferate more intensely so as to regenerate the injured tissue. Same goes with cancer -- tumor cells may be all but eliminated by radiation therapy and/or chemotherapy, only to return even more aggressively some time later.

Having a hormonal intrauterine device (IUD) implanted immediately after birth does not affect a woman's ability to lactate and breastfeed, according to new research by investigators at University of Utah Health and University of New Mexico School of Medicine. The results of this study are available online August 21 in the American Journal of Obstetrics and Gynecology.

Patients perceive no significant change in the quality of care for cancer since the United States’ government passed the Medicare Prescription Drug, Improvement, and Modernization Act of 2003 (MMA) according to a study published in the November 15, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society.