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Abelacimab Effective Blood Clot Treatment, McMaster-led Study Shows

Science 2.0 - Jan 11 2024 - 14:01

Hamilton, ON (July 19, 2021) - A potentially game-changing treatment for people with, or at risk of, blood clots has been found effective by an international team of researchers led by McMaster University's Jeffrey Weitz.

Weitz's team compared abelacimab with enoxaparin as a control drug in 412 patients undergoing knee replacement surgery. Results showed that just one abelacimab injection prevents blood clots for up to a month after surgery, reducing the risk by about 80% compared with enoxaparin without increasing the risk of bleeding.

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Tianeptine And Other Supplements Have Gotten An FDA Free Pass For 30 Years - It's Time For That To End

Science 2.0 - Jan 11 2024 - 14:01
Politics is about trade-offs. Perhaps a reason President Biden isn't better-regarded is because if Congress didn't give him what he wanted, he circumvents them with agencies he controls, such as OSHA with vaccine mandates, the CDC with rent control, and EPA to ban safe weedkillers and pesticides.

He can take a page out of Presidents Clinton and Bush 43 on how to do better if he wins again this fall.

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Mayo Research Provides Insights Into High-risk Younger Demographics For Severe COVID-19

Science 2.0 - Jan 11 2024 - 14:01

ROCHESTER, Minn. ? Using data from 9,859 COVID-19 infections, Mayo Clinic researchers have new insights into risk factors for younger populations, some of which differ significantly from their older counterparts. People younger than 45 had a greater than threefold increased risk of severe infection if they had cancer or heart disease, or blood, neurologic or endocrine disorders, the research found. These associations were weaker in older age groups. The study was published in Mayo Clinic Proceedings.

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Public Health Summer Program Increases STEM Career Interests In High Schoolers

Science 2.0 - Jan 11 2024 - 14:01

High school students who participated in summer programs about public health increased their interest in pursuing careers in science, technology, engineering and mathematics (STEM), according to a Rutgers study.

Published in the journalPedagogy in Health Promotion, the study explored whether increasing public health awareness would motivate high school students to pursue public health careers.

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EHT Pinpoints Dark Heart Of The Nearest Radio Galaxy

Science 2.0 - Jan 11 2024 - 14:01

An international team anchored by the Event Horizon Telescope (EHT) Collaboration, which is known for capturing the first image of a black hole in the galaxy Messier 87, has now imaged the heart of the nearby radio galaxy Centaurus A in unprecedented detail. The astronomers pinpoint the location of the central supermassive black hole and reveal how a gigantic jet is being born. Most remarkably, only the outer edges of the jet seem to emit radiation, which challenges our theoretical models of jets.

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More Exercise And Fewer Hours Watching TV Cuts Sleep Apnoea Risk

Science 2.0 - Jan 11 2024 - 14:01

Being more physically active and spending fewer hours per day sitting watching TV is linked to a substantially lower risk of developing obstructive sleep apnoea (OSA), according to new research published in the European Respiratory Journal [1]. It is the first study to simultaneously evaluate physical activity and sedentary behaviour in relation to OSA risk.

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Urgent Need For Anti-smoking Campaigns To Continue After Pregnancy

Science 2.0 - Jan 11 2024 - 14:01

Curtin University research has found quit support for smoking mothers should continue even after their first babies are born, given that many of those women will become pregnant again, and that quitting can substantially reduce the risk of future preterm births.

The longitudinal study examined the records and histories across 23 years, of 63,540 Australian women with more than one child, who smoked during their first pregnancy.

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Gene Expression Mechanism May Have Immunity, Cancer Implications

Science 2.0 - Jan 11 2024 - 14:01

PHILADELPHIA -- (July 20, 2021) -- Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance of APA was poorly understood. Now a new study by The Wistar Institute describes an important function of APA in allowing certain mRNAs to reach specific sites of protein synthesis and reveals that length, sequence and structural properties can determine the destination (and fate) of mRNAs within the cell.

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Climate Change Threatens Food Security Of Many Countries Dependent On Fish

Science 2.0 - Jan 11 2024 - 14:01

Millions of people in countries around the world could face an increased risk of malnutrition as climate change threatens their local fisheries.

New projections examining more than 800 fish species in more than 157 countries have revealed how two major, and growing, pressures - climate change and over-fishing - could impact the availability of vital micronutrients from our oceans.

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Bleak Cyborg Future From Brain-computer Interfaces If We're Not Careful

Science 2.0 - Jan 11 2024 - 14:01

WASHINGTON, July 20, 2021 -- Surpassing the biological limitations of the brain and using one's mind to interact with and control external electronic devices may sound like the distant cyborg future, but it could come sooner than we think.

Researchers from Imperial College London conducted a review of modern commercial brain-computer interface (BCI) devices, and they discuss the primary technological limitations and humanitarian concerns of these devices in APL Bioengineering, from AIP Publishing.

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Data Identifies Turbine Wake Clustering, Improves Wind Farm Productivity Via Yaw Control

Science 2.0 - Jan 11 2024 - 14:01

WASHINGTON, July 20, 2021 -- In the wind power industry, optimization of yaw, the alignment of a wind turbine's angle relative to the horizonal plane, has long shown promise for mitigating wake effects that cause a downstream turbine to produce less power than its upstream partner. However, a critical missing puzzle piece in the application of this knowledge has recently been added -- how to automate the identification of which turbines are experiencing wake effects amid changing wind conditions.

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Babies At Risk For Diabetes May Have Microbiota Restored

Science 2.0 - Jan 11 2024 - 14:01

Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a Rutgers study.

The study, which involved genetic analysis of mice, appears in the journal Cell Host & Microbe.

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Risk Score With 6 Routinely Available Lab Tests Accurately Predicts Kidney Failure

Science 2.0 - Jan 11 2024 - 14:01

Researchers developed a new risk equation, based on six routinely available patient parameters, that yielded improved performance in estimating the risk of a chronic kidney disease (CKD) patient to progress to end-stage kidney disease (ESKD) requiring kidney replacement therapy (KRT).

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Most Studies Of Acute Kidney Injury Are Flawed Due To Non-use Of Standard Definitions

Science 2.0 - Jan 11 2024 - 14:01

In an article published in the American Journal of Kidney Diseases (AJKD), researchers found that among 176 studies on acute kidney injury, the Kidney Disease Improving Global Outcomes (KDIGO) definitions of kidney injury were inconsistently applied and 80% of studies did not define recovery of kidney function.

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SARS-CoV-2 Spike Mutation L452R Evades Human Immune Response And Enhances Infectivity

Science 2.0 - Jan 11 2024 - 14:01

An international team of researchers led by Kumamoto and Tokyo Universities (Japan) have shown that the L452R mutation of the SARS-CoV-2 spike protein, which is common to two mutant strains (Epsilon and Delta), is involved in cellular immunity evasion via the human leukocyte antigen (HLA) A24, and enhances viral infectivity.

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This Is How The Visual System Shows Us A More Persistent World

Science 2.0 - Jan 11 2024 - 14:01

An international collaboration elucidates the mechanisms that facilitate accurate identification of moving images. The findings have been published in Nature Communications

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Increased Physical Activity After ICD Implantation Linked To Less Hospitalization, Death

Science 2.0 - Jan 11 2024 - 14:01

DALLAS, July 21, 2021 -- People who made even small increases in their daily physical activity levels after receiving an implantable cardioverter defibrillator (ICD) experienced fewer incidences of hospitalization and had a decreased risk of death, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

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Breastfeeding, Even For A Few Days, Linked To Lower Blood Pressure In Early Childhood

Science 2.0 - Jan 11 2024 - 14:01

DALLAS, July 21, 2021 -- Babies who were breastfed, even for a few days, had lower blood pressure as toddlers and these differences in blood pressure may translate into improved heart and vascular health as adults, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

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Virginia Tech's COVID-19 Testing Demonstrates Power, Versatility Of Academic Labs

Science 2.0 - Jan 11 2024 - 14:01

In the early days of the pandemic, scientists at Virginia Tech created a COVID-19 testing laboratory and novel test for the virus from scratch.

They not only developed a test in-house that avoided the reagent supply shortages that hampered testing efforts nationwide, but also used 3D-engineered supplies and stable storage media, enabling samples to be transported to rural sites in Virginia without the need for constant refrigeration.

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A Substance From Saussurea Controversa Will Help Bone Tissue Regeneration

Science 2.0 - Jan 11 2024 - 14:01

Metabolic bone diseases, including osteoporosis, when bones lose their mass and become so fragile that they could be damaged while sneezing or under little stress, are called the silent epidemic of the 21st century. A person does not even know about his illness before the first symptom - it can be a fracture of the spine or the neck of the hip. According to statistics, every third woman and every fifth man after 50 have osteoporosis.

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