Drug discovery is a long, tortuous and impossibly difficult job. A group at the University of Warwick has come up with a mathematical model that seems to be a very big step in streamlining the process. But is it really? To answer this we need to take a look at how drugs are discovered.
The long-term problems of a transvaginal mesh shed light on a difficulty with the FDA's concept of 'substantial equivalence' in approving some medical devices.
It's the season for Top 10 lists. The challenge, as usual, is to narrow down all the junk science we debunked in 2017 to just the ten best (worst?) stories. It would be far easier to create a top 100 list.
Older folks are going to fall.
It's a fact of life, just like the emergence of slick sidewalks in the winter. And catching your shoe on a rug, which you've had for 30 years ago but somehow appeared out of nowhere.
Since this holiday season America is caught in the midst of a cultural miasma, where people are confused about what is acceptable sexual harassment and what is not, along with the usual recurring concerns about commercialization, I am compiling some practical guidance. I want to wish you a Ron Swanson Christmas.
Here are the final four exciting developments in science, health and technology of 2017. And, a prediction for what innovation could be truly disruptive in the future.
Words matter. I would like more patients and fewer healthcare consumers - it is such a harsh term, all about taking.
Over the past few days, a controversy has erupted following reports in the Washington Post that the Trump Administration has banned or otherwise discouraged the use of seven words, such as "fetus" and "transgender," by the CDC and other HHS agencies. For what it's worth, CDC Director Brenda Fitzgerald has denied these reports.
Earning in living in science has been "uneven" (let's be kind) over the past 15 years. In 2008, in the middle of what would be known as the Great Recession, a chemist with the pseudonym Chemjobber started a blog about finding science jobs. He is now widely followed and we thank him for speaking with us about his experience.
Drugs submitted to the FDA for approval must have safety and efficacy data for the condition they are designed to treat. Sometimes, however, a drug is found to be effective for another condition, and doctors are within their rights to prescribe it for such "off-label" uses. Such may soon be the case for metformin, which has been shown to be useful in preventing some types of breast cancer cells from developing resistance to the drugs used to treat them — at least in mice.
As if GOOP in the United States is not bad enough, Gwyneth Paltrow's "lifestyle" brand is crossing the northern border. Soon, GOOP products will be available, by shipping, to Canadians.
What this means is that, despite serving as a late night talk show object of ridicule, GOOP is gaining in popularity.
The CDC is told seven words are no longer allowed in their documents. Banning words and thoughts doesn't work, just ask George Carlin. Do they think it will somehow work now?
Medical researchers studying CTE, or chronic traumatic encephalopathy, are working to learn more about this degenerative brain disease. While definitive diagnosis is currently only possible post-mortem, the study of this ever-more visible disease includes the push to learn about its presence in the living.
The recent revelations from Larry Johnson, a 38-year-old former NFL running back, who says he thinks he's currently experiencing symptoms of CTE, may shed light in that regard.
Waze, a driving navigation app has moved from traffic advisor to traffic director as it's user base grows. Does this new algorithmic overlord have special responsibilities?
Just about 10 years ago, ACSH published the first edition of our booklet Celebrities VS Science, calling out a number of well-known personalities for promulgating non-scientific nonsense. Unfortunately, that trend has continued, as a new essay points out.
Somebody is pulling a conceptual fast-one over those gullible enough to believe it, both on and off the ice. It's the selling of a false reality, rooted in a baseless premise that changing a uniform's color can make athletes skate faster. Absurd doesn't begin to describe this.
For people living with celiac disease, everything that goes into the body has to be assessed for gluten. Even tiny amounts (trace amounts) of gluten can cause illness in some people with celiac disease. In order to do that, people need to know what they are putting into their bodies.
The FDA really doesn't want you taking pain meds. How strong is the agency's position on this? Pretty strong. Enough so to recommend that physicians receive extra education in alternative pain management methods. That's fine, but one of them is acupuncture, which is not at all fine. Dr. Paul Offit explains.
Recently, ACSH 's Director of Medicine Dr. Jamie Wells filmed a segment on the top medical, science and technology innovations of 2017 at Reuters TV in Times Square, New York with host of CCTV Bianca Chen.
Wasting food, a precious resource, is bad. Does French regulation make for less waste or could there be an equally simple free-market solution?