Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem cells.
In contrast to the ease of targeted gene deletion, the complementary application, called targeted gene cassette insertion or knock-in, in fertilized mouse eggs by CRISPR/Cas mediated genome editing still remains a tough challenge.
Chipotle wins the science ‘foot in mouth’ award for 2015, and we are not even to summer yet. So far there are more than 40 media condemnations and counting.
The fast food chain’s “bold” move, announcing a faux ban on GMOs in its food, has blown up big time. Why faux? Because, as Chipotle well knows, its sodas, beef, pork and chicken dishes, and any food with cheese, are made with ingredients that were derived through genetic engineering.-->
Even before Jacqueline Ho enrolled in her first environmental studies course at college, her thinking about climate change had been shaped during her years growing up in Singapore reading books by the environmental writer and activist Bill McKibben.
At college, ideas first planted by McKibben were reinforced in courses where she read classics by Aldo Leopold and Garrett Hardin, along with recent books by Van Jones and Elizabeth Kolbert.
With these authors anchoring her understanding, it was easy for Ho to believe about climate change “that fossil fuel corporations were to blame, that we had a suite of low-carbon technologies we could deploy immediately, and that grassroots solutions held promise,” she recalls.-->
Researchers are reporting that pancreatic cancer rates are highest in countries with the least amount of sunlight, due to a combination of heavy cloud cover and high latitude.
Researchers have developed and used a new technique to connect the dots in the genomic puzzle. Just as dots have to be connected to visualize a full picture, the researchers connected regulatory elements called promoters and enhancers and showed their physical interactions over long distances within the mouse and human genomes.
The ability to map promoter-enhancer interactions in the human genome has huge potential in understanding the genetic basis of disease.
Proper clinical research exposure in medical school is a somewhat modern invention. Prior to changes implemented by Harvard Medical School in the 19th century, medicine was more application-focused, but gradually medical schools began to expose students to basic and clinical research. By the 20th century it was the norm that doctors would have a foundation in research and physician-scientists were their teachers.
A new soybean with significantly reduced levels of three key proteins responsible for both its allergenic and anti-nutritional effects has been created. Soybean is a major ingredient in many infant formulas, processed foods and livestock feed used for agriculture.
Perhaps Lance Armstrong needs to get his Tour de France victories back - a new study shows that winning all of those may not have been because of performance-enhancing drugs, it may have been spite of them, which would make his successes all that more amazing.
Two ocean hot spots have been linked to the hottest summers on record for the central United States, in 1934 and 1936. Those two summers and the "Dust Bowl" that saw farming devastated were accompanied by the worst drought in America of the last 1,000 years.
In 1934, giant dust storms and drought covered more than 75 percent of the country and affected 27 states severely. Silt from storms even covered the decks of ships 200 miles off the east coast.
In biology class you learned that DNA (deoxyribonucleic acid) is the main component of our genetic material and it is formed by combining four parts: A, C, G and T (adenine, cytosine, guanine and thymine), called bases of DNA. These bases combine in thousands of possible sequences to provide the genetic variability that enables the wealth of aspects and functions of living beings.
In the early 1980s, the four "classic" bases of DNA sort of got a fifth - methyl-cytosine (mC), derived from cytosine, which was later linked to epigenetic mechanisms because it is able to switch genes on or off depending on the physiological needs of each tissue.
Scholars say they have found a way to prevent procrastination.
The trick? Think of the future as now. If you decide you will read this article tomorrow, you are already behind.
Making a series of relatively minor and realistic changes to UK diets would reduce UK diet-related greenhouse gas emissions by nearly 20 percent and extend average life expectancy by eight months, according to new model.
Producing sperm is necessary to procreate and but procreation only happens the first time in those birth control public awareness films. In most cases, sperm must be produced continuously, and for an extended period of time, to insure reproduction.
A new study reveals that there are differences in reactivity to retinoic acid in spermatogonial stem cells, and these differences are a key factor to the persistence of sperm production with inexhaustible stem cells.
The latest article exploring sexism in academia suggests that it no longer exists. Some have already grumbled about flaws in the study’s design. But more than that, I simply don’t believe the finding because there is clear evidence that sexism still exists.-->