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Viruses are the most common cause of myocarditis in children, experts offer guidance
Viral infection is the most common cause of inflammation in the heart muscle, called myocarditis, in children; however, there remains a diverse array of infectious and non-infectious causes of myocarditis that should be considered in diagnosis.Myocarditis caused by a virus is more often seen in children than in adults, and children are more likely to have acute myocarditis (sudden onset) rather than chronic myocarditis, which is more typically seen in adults.
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Rare genetic variants confer largest increase in type 2 diabetes risk seen to date
Scientists at the University of Cambridge have identified rare genetic variants - carried by one in 3,000 people - that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect.
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New approach will help identify drugs that can 'glue' proteins together
A new screening method that can test the effectiveness of therapeutic molecules designed to 'glue' proteins together in the body has been developed by researchers at the University of Birmingham and the University of Leicester.
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Understanding frailty will lead to better care for older adults
A team led by researchers from the University of Waterloo, which analyzed data from more than 24,000 community-dwelling older adults receiving home care in Ontario who were subsequently admitted into an intensive-care unit, have found that frailty is a better predictor than factors such as age when determining how older adults fare one year after receiving critical care.
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Brain functional connectivity in Tourette syndrome
Tourette syndrome, a neurodevelopmental disorder, causes motor and phonic "tics," or uncontrollable repeated behaviors and vocalizations. People affected by Tourette syndrome can often suppress these tics for some time before the urges become overwhelming, and researchers have long wondered at the neural underpinnings of the suppression effort. In a new study, researchers at Yale School of Medicine have assessed the impact of tic suppression on functional connectivity between brain regions.
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New model accurately predicts how coasts will be impacted by storms and sea-level rise
Scientists at the University of Plymouth have developed a simple algorithm-based model which accurately predicts how coastlines could be affected by extreme storms and predicted rises in sea levels and - as a result - enables communities to identify the actions they might need to take in order to adapt.
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Why wild African fruits can supplement low protein staple foods
Wild fruits from Southern Africa show good potential to supplement diets with the building blocks of protein. Researchers from the University of Johannesburg studied 14 species. Two of the fruits contain several essential amino acids. All exceed the RDA for lysine. People can only obtain lysine from their food or supplements. Healthy development in children requires lysine. Maintaining a robust immune function also needs it, especially against viruses.
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Transformation of controller software to ensure safe behavior under perceptual uncertainty
A team at National Institute of Informatics, Japan and University of Waterloo developed a method that automatically transforms models of controller software into models that satisfy safety requirements even when uncertainty in sensing the state of the environment. In addition, the method generates formulas that represent the degree of uncertainty that the controller software can tolerate. The method can be applied to various controller systems that interact with the external environment, including autonomous vehicles.
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Oncotarget: miRNA signatures from epidermal growth factor inhibitor patients
This Oncotarget study suggests that miR-21, miR-31 and miR-520e expression might be a treatment dependent marker for EGFRI induced skin rash.
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Gender pay gap means fewer female candidates on the ballot
A new study in the Journal of the European Economic Association, published by Oxford University Press, finds that electoral districts with a larger gender pay gaps show favoritism toward male political candidates in Parliamentary elections, with fewer female candidates on the ballot.
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Could a longer reproductive period put women at greater risk for Alzheimer disease?
Estrogen has been thought to play a role in a woman's risk of developing Alzheimer disease (AD). A new study has taken a different approach to identifying risk factors for AD by examining the association between a woman's reproductive life span as an indicator of endogenous estrogen exposure and levels of cerebrospinal fluid biomarkers. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS).
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New method lets researchers rapidly monitor snow leopard stress levels in the wild
A new method developed by a Kyoto University researcher is the first to allow users to analyse snow leopard stress hormones in the field. The findings are published in the British Ecological Society journal, Methods in Ecology and Evolution.
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PcFe-catalyzed radical phosphinoylazidation of alkenes with fast azido transfer step
The first iron-catalyzed phosphinoylazidation of alkenes under relatively mild reaction conditions affording compounds containing nitrogen and phosphorus is reported. This method is practically useful to deliver the azidophosphonates and requires relatively low loading of catalyst. Mechanistic studies confirmed the radical nature of the reaction and disclosed the unusually low activation energy 4.8 kcal/mol of radical azido group transfer from the azidyl iron(III) phthalocyanine species (PcFeIIIN3) to a benzylic radical rather than from the high-valent PcFeIV(N3)(Radical) species.
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UK public view COVID-19 as a threat because of lockdowns, new study suggests
A project led by the universities of Bath, Cardiff and Essex finds people judge pandemic risk by magnitude of policy response
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UT Southwestern scientists closing in on map of the mammalian immune system
Using artificial intelligence, UT Southwestern scientists have identified thousands of genetic mutations likely to affect the immune system in mice. The work is part of one Nobel laureate's quest to find virtually all such variations in mammals.
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Methane in the plumes of Saturn's moon Enceladus: Possible signs of life?
A study published in Nature Astronomy concludes that known geochemical processes can't explain the levels of methane measured by the Cassini spacecraft on Saturn's icy moon. While the paper by no means suggests that life exists on Enceladus, the results would be consistent with microbial activity similar to that known to occur at hydrothermal vents in Earth's oceans.
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Still waiting at an intersection? Banning certain left turns helps traffic flow
When traffic is clogged at a downtown intersection, there may be a way to reduce some of the congestion: Eliminate a few left turns.
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mRNA vaccines slash risk of COVID-19 infection by 91% in fully vaccinated people
People who receive mRNA COVID-19 vaccines are up to 91 percent less likely to develop the disease than those who are unvaccinated, according to a new nationwide study of eight sites, including Salt Lake City. For those few vaccinated people who do still get an infection, or "breakthrough" cases, the study suggests that vaccines reduce the severity of COVID-19 symptoms and shorten its duration.
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SAEM publishes GRACE guidelines for recurrent, low-risk chest pain care in the ED
The Society for Academic Emergency Medicine (SAEM) is pleased to announce the release of the first publication in a series of Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE), which focuses on low-risk chest pain.
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One in four adults with depression or anxiety lack mental health support during pandemic
A new national study published in Psychiatric Services finds that over a quarter of US adults with depression or anxiety symptoms reported needing mental health counseling but were not able to access it during the COVID-19 pandemic. Researchers analyzed data from nearly 70,000 adults surveyed in the US Census Household Pulse Survey in December 2020.
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