Feed aggregator

Researchers at the University of Chicago's Pritzker School of Molecular Engineering and Biological Sciences Division have developed a combined imaging and machine learning technique that can, for the first time, measure a metabolic process at both the cellular and sub-cellular levels.

The surface of a material often has properties that are very different from the properties within the material. An international research team from the University of Göttingen, the Max Planck Institute for Biophysical Chemistry Göttingen and the National Research Council Canada has now succeeded in investigating the surfaces of transparent crystals using powerful irradiation from lasers. The results of the study were published in the journal Nature Communications.

MIAMI--In a new analysis on managed retreat--the climate adaptation response of moving people and property out of harm's way--researchers explore what it would take for managed retreat to be supportive of people and their priorities. A key starting point is considering retreat alongside other responses like coastal armoring and not just as an option of last resort.

Researchers at the University of Houston, in collaboration with Rice University, published a paper detailing how to improve energy density in a novel electric vehicle battery - a step toward a more cost-effective, easily recycled battery that would allow EVs to travel farther and charge faster at a low cost.

A rare parasitic infection imported from Europe continues to take root in Alberta. The province is now the North American hotspot for human alveolar echinococcosis (AE), which takes the form of a growth in the liver, causing serious and potentially deadly health complications.

Anti-science attitudes and political ideology often go hand in hand, a new USC study finds, which means machine-analyzed data on platforms such as Twitter could offer clues as to where diseases like COVID-19 might spread.

Purdue innovators have created a biosensor that allows for simultaneous recording and imaging of tissues and organs during a surgical operation. Traditional methods to simultaneously record and image tissues and organs have proven difficult because other sensors used for recording typically interrupt the imaging process. The ultra-soft, thin and stretchable Purdue biosensor is capable of seamlessly interfacing with the curvilinear surface of organs even under large mechanical deformations.

Despite near unanimous objection from its advisory panel, the US Food and Drug Administration (FDA) granted aducanumab approval to treat Alzheimer's disease on June 7, 2021. In a commentary published in Annals of Internal Medicine, a member and former Chair of the advisory panel and an aducanumab site investigator explain why this unprecedented "accelerated approval" is problematic for clinical research and patient care.

In the international prospective multicenter crossover LEADER-75 trial, comparison of reduced-dose gadobutrol and standard-dose gadoterate versus unenhanced imaging demonstrated noninferiority using 20% margin for three primary efficacy measures; mean readings differed by less than 1%, supporting equivalence using a narrow ±5% margin. Various secondary variables also supported non-inferiority of reduced-dose gadobutrol.

An algorithm designed by researchers from Carnegie Mellon University's Computational Biology Department and St. Petersburg State University in Russia could help scientists identify unknown molecules. The algorithm, called MolDiscovery, uses mass spectrometry data from molecules to predict the identity of unknown substances, telling scientists early in their research whether they have stumbled on something new or merely rediscovered something already known. This development could save time and money in the search for new naturally occurring products that could be used in medicine.

In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

UC San Diego School of Medicine researchers discovered that the enzyme RNA polymerase II recognizes and transcribes artificially added base pairs in genetic code, a new insight that could help advance the development of new vaccines and medicines.

Forest fires have crept higher up mountains over the past few decades, scorching areas previously too wet to burn, according to researchers from McGill University. As wildfires advance uphill, a staggering 11% of all Western US forests are now at risk.

Patients with blood cancers who were hospitalized with COVID-19 fared better if they were given convalescent plasma, according to study findings from a consortium that included the Mays Cancer Center, home to UT Health San Antonio MD Anderson.

Geothermal energy systems have the potential to power the world and become the leading technology for reducing greenhouse gas emissions if we can drill down far enough into the Earth to access the conditions necessary for economic viability and release the heat beneath our feet. Quaise Inc. is developing a potentially disruptive drilling technology to make that happen. Matt Houde of Quaise presented the approach at the World Geothermal Congress on June 15.

Additive manufacturing offers an unprecedented level of design flexibility and expanded functionality, but the quality and process can drastically differ across production machines, according to Hui Yang, a professor of industrial engineering at Penn State. With applications in aerospace, health care and automotive industries with potential for mass customization, additive manufacturing needs quality management.

By cleverly combining complementary sequencing techniques, researchers of Ghent University, together with Baylor College of Medicine and the world's leading sequencing company, Illumina, have deepened our understanding of the function of known RNA molecules and discovered thousands of new RNAs. A better understanding of our transcriptome is essential to better understand disease processes and uncover novel genes that may serve as therapeutic targets or biomarkers.

With sorghum poised to become an important crop grown by Pennsylvania farmers, Penn State researchers, in a new study, tested more than 150 germplasm lines of the plant for resistance to a fungus likely to hamper its production.

In research published today in Nature Nanotechnology, a team of materials scientists and engineers, led by Jian Shi, an associate professor of materials science and engineering at Rensselaer Polytechnic Institute, used a strain gradient in order to break inversion symmetry, creating a novel optoelectronic phenomenon in the promising material molybdenum disulfide (MoS2) -- for the first time.

Superconductors have tremendous appeal in power transmission applications due to their zero resistance. However, to bring classical metallic superconductors into superconducting state requires liquid helium as a coolant, which is costly. Now, scientists from Japan take things to the new level by demonstrating high temperature superconductivity in mixed rare-earth barium copper oxides fabricated using a popular technique, opening doors to their low-cost, industrial scale production for real-world applications.