Scientists at the University of Copenhagen, led by the Spanish Professor Guillermo Montoya, are investigating the molecular features of different molecular scissors of the CRISPR-Cas system to shed light on the so-called 'Swiss-army knives' of genome editing. Montoya's research group has visualized the atomic structures of the Cpf1 and Cas9 proteins to analyse each of their properties and peculiarities that make them ideal for different applications in gene modification.
A new study of four South Asian countries argues that early marriage should be considered a major public health issue, due to its complex associations with women's education, health and nutrition -- which may also affect the next generation of children. The study also finds that increased education has had some, but not enough, success in delaying girls' marriage.
In the largest study of its kind, researchers from the University of Bristol have analysed mood indicators in text from 800 million anonymous messages posted on Twitter. These tweets were found to reflect strong patterns of positive and negative moods over the 24-hour day.
Young people are less likely to try cigarettes with the printed health warning 'Smoking kills' on each stick than standard cigarettes, according to a new study by Cancer Research UK published in Nicotine & Tobacco Research.
In late December 2014, a submarine volcano in the South Pacific Kingdom of Tonga erupted, sending a violent stream of steam, ash and rock into the air. The ash plumes rose as high as 30,000 feet (9 kilometers) into the sky, diverting flights. When the ash finally settled in January 2015, a newborn island with a 400-foot (120-meter) summit nestled between two older islands -- visible to satellites in space.
Researchers have presented the association between tumor response and health-related quality of life in patients with metastatic Merkel cell carcinoma treated with avelumab.
As previously informed, the Phase III trial, ADMYRE, which compared plitidepsin in combination with dexamethasone versus dexamethasone alone met its primary endpoint, progression free survival, and secondary objectives, overall survival and safety
In several recent papers, researchers from MIT's Computer Science and Artificial Intelligence Laboratory (CSAIL) and the Qatar Computing Research Institute have used a recently developed interpretive technique, which had been applied in other areas, to analyze neural networks trained to do machine translation and speech recognition.
Rice University scientists discovered that adding a bit of water to asphalt-derived porous carbon greatly improves its ability to sequester carbon dioxide, a greenhouse gas, at natural gas wellheads. The filter is highly selective for carbon dioxide while letting methane pass through.
A comprehensive assessment of cheetah populations in southern Africa supported by the National Geographic Society reveals the dire state of one of the planet's most iconic big cats. In a study published today in the open-access journal PeerJ, researchers present evidence that low cheetah population estimates in southern Africa and population decline support a call to list the cheetah as 'Endangered' on the International Union for Conservation of Nature (IUCN) Red List.
Scientists have built a miniature scaffold inside bacteria that can be used to bolster cellular productivity, with implications for the next generation of biofuel production.Because there is a growing need for agricultural or renewable production of biofuels and other commodity chemicals to move away from fossil fuels, scientists have long sought to enhance the internal organisation of bacteria and improve the efficiency of the cells for making nutrients, pharmaceuticals and chemicals.
The best decisions are made on the basis of the average of various estimates: this has been confirmed by the research of Dennie van Dolder and Martijn van den Assem, scientists at VU Amsterdam. Using data from Holland Casino promotional campaigns, they have researched whether it is true that when people make estimates, the average of their estimates is relatively close to reality. The results of the research are being published today in Nature Human Behaviour.
Three million years ago, the sun shone weaker, but Earth stayed surprisingly warm. Carl Sagan thought a greenhouse effect must have been to thank. A model built on 359 chemical processes has finally arrived at scenarios with a reasonable chance of producing the needed methane on ancient Earth. The model has broad parameters in hope that it may someday be of use to interpret conditions on exoplanets.
Researchers have developed new single-cell sequencing methods that could be used to map the cell origins of various brain disorders, including Alzheimer's, Parkinson's, schizophrenia and bipolar disorder. By analyzing individual nuclei of cells from adult human brains, researchers have identified 35 different subtypes of neurons and glial cells and discovered which of these subtypes are most susceptible to common risk factors for different brain diseases.
Nearly half of the people who enrolled in Medicaid after it expanded in Michigan have jobs, a new study finds. Another 11 percent can't work, likely due to serious physical or mental health conditions. And about 1 in 4 enrollees are out of work but also are much more likely to be in poor health. The new findings may inform discussions of potential work requirements for poor and near-poor Americans who qualify for expanded Medicaid.
A fundamental advance in the quality of an optical material used to make hyperlenses makes it possible to see features on the surface of living cells in greater detail than ever before.
We use specialized nerve cells for spatial orientation. The place cells fire whenever we stay in a particular place. The grid cells, on the other hand, measure distances and play a crucial role in path integration. So much for the theory. Scientists from the German Cancer Research Center (DKFZ) and the University Hospital Heidelberg have now, for the first time, provided experimental proof of this.
In a world-first, a research team of Australian and international scientists has used data collected by satellites and an ocean model to explain and predict biodiversity on the Antarctic seafloor.
Offering new mothers financial incentives may significantly increase low breastfeeding rates, new research from the University of Sheffield and the University of Dundee has found.
University of Leeds researchers have mathematically examined plasma jets from supermassive black holes to determine why certain types of jets disintegrate into huge plumes.