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Report calls for 'comprehensive action' to tackle poverty in UK city

Eurekalert - Jun 08 2021 - 00:06
Rising unemployment, inadequate benefits and low paid work are the main causes of poverty and destitution in Stoke-on-Trent according to the findings of a new study.
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New study: Developers' skills and top management commitment lead to Agile project success

Eurekalert - Jun 08 2021 - 00:06
Which are the most compelling success factors of a large-scale Agile software transformation? And how do these factors relate? A new long-term study from Aalborg University highlights the stakeholders' roles in such transformations. The main result is a valuable model for software managers to set up and effectively manage the transformation of organisations.
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Exercise likely to be best treatment for depression in coronary heart disease

Eurekalert - Jun 08 2021 - 00:06
A study by RCSI indicates that exercise is probably the most effective short-term treatment for depression in people with coronary heart disease, when compared to antidepressants and psychotherapy or more complex care.
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Tree diversity may save the forest: Advocating for biodiversity to mitigate climate change

Eurekalert - Jun 08 2021 - 00:06
When it comes to climate change, policymakers may fail to see the trees for the forest. Turns out that the trees may be the answer after all, according to a study published by authors from more than seven countries on June 3 in Nature Climate Change.
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A genomic single-cell map explains neuronal death in epilepsy

Eurekalert - Jun 08 2021 - 00:06
A multidisciplinary team led by researchers from the Spanish Research Council (CSIC) identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy. The study, published in Cell Reports, identifies cell-type specific transcriptional signatures of hyper-excitability and neurodegeneration, providing grounds for improved diagnosis.
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Motor neurons derived from patients point to new possible drug target for ALS

Eurekalert - Jun 08 2021 - 00:06
Researchers at Boston Children's Hospital, working in collaboration with Pfizer, now report a high-throughput target and drug discovery platform using motor neurons made from ALS patients. Using the platform, they confirmed two known targets and identified an existing class of drugs -- agonists to the dopamine D2 receptor -- as potential novel treatments.
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Gap between death rates in rural and urban areas tripled during past two decades

Eurekalert - Jun 08 2021 - 00:06
Researchers find that age-adjusted mortality rates (AAMRs) declined in both rural and urban populations, but that the gap between the death rates dramatically widened as white individuals aged 25 to 64 in rural areas faced increasing AAMRs.
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The next 20 are years crucial in determining the future of coal

Eurekalert - Jun 08 2021 - 00:06
Decisions made now will determine whether economies win or lose money as the coal industry changes over the next couple of decades.
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Don't skip your routine check-up; here's why

Eurekalert - Jun 08 2021 - 00:06
The benefits of routine primary care doctor visits include chronic illness detection, cancer screenings and therefore should continue, despite some calls from healthcare leaders saying they're a waste of time. For at-risk populations, the check-ups are still vital, and all patients on Medicare and many insured patients pay $0 copay for annual wellness checks.
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Patient characteristics, subsequent health care use of SARS-CoV-2 testing initiation in safety-net health system

Eurekalert - Jun 08 2021 - 00:06
Researchers found differences in sociodemographic and clinical characteristics by entry location for SARS-CoV-2 testing within a safety-net health system. White and English-speaking individuals disproportionately initiated testing via telehealth visits, while black, Native American and non-English-speaking patients disproportionately initiated testing through the emergency department. 
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Risk factors associated With COVID-19 outcomes among people with intellectual, developmental disabilities receiving residential services

Eurekalert - Jun 08 2021 - 00:06
This study tracked COVID-19 outcomes for 543 individuals with intellectual and developmental disabilities who were receiving support services from an organization providing residential services in the five boroughs of New York.
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Associations of race/ethnicity and food insecurity with COVID-19 infection rates

Eurekalert - Jun 08 2021 - 00:06
What The Study Did: The findings of this observational study of the association of race/ethnicity with COVID-19 infection rates and the interaction of pre-COVID experiences of food insecurity suggest that the association varied over time and across racial/ethnic groups.
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Balancing speech intelligibility, face covering effectiveness in classrooms

Eurekalert - Jun 08 2021 - 00:06
A better understanding of the impacts of face masks and shields on acoustic transmission in classrooms could help optimize educational settings. During the 180th ASA Meeting, Laura and Rich Ruhala from Kennesaw State University will talk about how various types of face coverings may affect students' understanding of their teacher. Their presentation, "Acoustical transmission of face coverings used to reduce coronavirus transmission in a classroom environment," will take place Tuesday, June 8, 2021.
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Human brain replays new memories at 20 times the speed during waking rest

Eurekalert - Jun 08 2021 - 00:06
Neural replay during waking rest may contribute to memory consolidation of action sequences in humans, according to a study published June 8 in the journal Cell Reports. Brain imaging results revealed fast, repeated reactivation of a neural network representing a behavioral sequence that people were learning -- approximately 20 times the speed of the new memory -- especially while they were taking breaks from practice.
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Scientists discover immune cell behavior that plays a key role in Alzheimer's disease

Eurekalert - Jun 08 2021 - 00:06
Immune cells in the brain, microglia, increase in number when encountering amyloid -- proteins which cause Alzheimer's disease. This increase in number turns some microglia 'senescent,' meaning they cannot carry out their immune functions correctly.Senescent microglia in turn accelerate the accumulation of amyloid, the opposite of what they intend to do.Preventing the proliferation of immune cells impairs senescence.Preventing senescence can then reduce build-up of amyloid and cell damage in the brain.
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A call for global oversight of unproven stem cell therapies

Eurekalert - Jun 08 2021 - 00:06
The promotion and marketing of unproven stem cell therapies is a global problem that needs a global solution, say experts in a perspective published June 8 in the journal Stem Cell Reports. The authors of the paper call for the World Health Organization (WHO) to establish an advisory committee on regenerative medicine to tackle this issue and provide guidance for countries around the world.
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Finding quasars: Rare extragalactic objects are now easier to spot

Eurekalert - Jun 08 2021 - 00:06
Astrophysicists from the University of Bath in the UK have developed a new method for pinpointing the whereabouts of extremely rare extragalactic objects. They hope their technique for finding 'changing-look quasars' will take scientists one step closer to unravelling one of greatest mysteries of the universe - how supermassive black holes grow. Quasars are believed to be responsible for regulating the growth of supermassive black holes and their host galaxies.
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Systematic literature review provides evidence base for new therapeutic avenues in vasculitis

Eurekalert - Jun 08 2021 - 00:06
Researchers have reviewed all clinical trials of targeted drugs used in the treatment of vasculitis. With this, they propose a completely mechanistic categorisation of these diseases, which may in time provide better treatment.
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Men with sensory loss are more likely to be obese

Eurekalert - Jun 08 2021 - 00:06
Men who suffer sensory loss, particularly hearing loss, are more likely to be physically inactive and obese than women, according to a new study published in the European Journal of Public Health.
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Porpoises seem to cooperate in surprisingly sophisticated group hunting

Eurekalert - Jun 08 2021 - 00:06
Drone footage shows that porpoises may be more social and cooperative than previously thought.
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