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COVID-19 symptom incidence among hospital employees for early alert surveillance of hospital admissions
What The Study Did: This study examined whether mandatory daily employee symptom data collection can be used as an early alert surveillance system to estimate COVID-19 hospitalizations in communities where employees live.
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Association of convalescent plasma therapy with survival in patients with blood cancers, COVID-19
What The Study Did: Researchers evaluated the association of convalescent plasma treatment with 30-day mortality in hospitalized adults with hematologic (blood) cancers and COVID-19.
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Differences in inpatient mortality among US Black, White patients with COVID-19
What The Study Did: The findings of this study suggest that the increased mortality among Black patients hospitalized with COVID-19 is associated with the hospitals at which Black patients disproportionately received care.
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Higher COVID-19 mortality among Black patients linked to unequal hospital quality
If Black patients were admitted to the same hospitals that serve a majority of White patients, researchers showed that their risk of death would drop by 10 percent.
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New manufacturing technique for flexible electronics
The long-sought future of flexible electronics that are wearable has proven elusive, but Stanford researchers say they have made a breakthrough.
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Antibiotic Novobiocin found to kill tumor cells with DNA-repair glitch
An antibiotic developed in the 1950s and largely supplanted by newer drugs, effectively targets and kills cancer cells with a common genetic defect, laboratory research by Dana-Farber Cancer Institute scientists shows. The findings have spurred investigators to open a clinical trial of the drug, novobiocin, for patients whose tumors carry the abnormality.
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Slowed cell division causes microcephaly
In primary microcephaly, the ballet of cell division is dysregulated, preventing proper brain development. Scientists (UNIGE) have demonstrated how the mutation of a single protein, WDR62, prevents the proper formation of the cable network responsible for separating genetic material into two. As cell division is then slowed down, the brain does not have time to build itself completely. These results shed new light on cell division, a phenomenon also involved in cancer development.
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Coelacanths may live nearly a century, five times longer than researchers expected
Once thought to be extinct, lobe-finned coelacanths are enormous fish that live deep in the ocean. Now, researchers reporting in the journal Current Biology on June 17 have evidence that, in addition to their impressive size, coelacanths also can live for an impressively long time--perhaps nearly a century.
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Predicting resistance to anticancer drugs
Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice' by the cancer cells may help us devise better therapeutic strategies. Now, the team of Prof. Jean-Christophe Marine (VIB-KU Leuven Center for Cancer Biology) shows that the presence of certain stem cells correlates with the development of nongenetic resistance mechanisms.
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Foresight diagnostics to show vision of the new standard of lymphoma MRD detection at ICML
Forsight to present clinical data of their blood-based MRD detection platform for DLBCL that detects relapse 200 days earlier than other methods.
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State of the art and future directions in the clinical application of HR-pQCT in adults
In recent years, significant progress has been made towards the use of high-resolution peripheral computed tomography (HR-pQCT) imaging in research, and new potential for applications in the clinic have emerged. This new publication by the Joint IOF-ASBMR-ECTS HR-pQCT Working Group provides an important overview of current clinical applications of HR-pQCT in adults, valuable guidance on interpretation of results, and a summary of novel applications and future directions.
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RUDN mathematician builds a COVID-19 spread model -- it shows how vaccination affects pandemic
RUDN University mathematicians built a model of COVID-19 spreading based on two regression models. The mathematicians divided the countries into three groups, depending on the spreading rate and on the climatic conditions, and found a suitable mathematical approximation for each of them. Based on the model, the mathematicians predicted the subsequent waves. The forecast was accurate in countries where mass vaccination was not introduced.
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Sensitive and specific detecting biomarker of radiation-resistant nasopharyngeal carcinoma
In our study, we constructed a detecting platform based on TpTta-COF nanosheets and fluorescent probe. The TpTta-COF nanosheets can adsorb single-stranded DNA (ss-DNA) probes and quench the fluorescence of ss-DNA. The method enables to capture miR-205 sensitively in aqueous solution with a detection limit of 4.78 nM in the range 0-500 nM and R2 = 0.989, and the method offers great specificity in that it can distinguish the target miRNA from mismatch non-target miRNAs.
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Bronze Age Scandinavia's trading networks for copper settled
500 years after the full implementation of copper technology in Scandinavia, the trade that brought the much needed copper to Denmark and southern Sweden also expanded across the Alps. At this time, Bronze Age Scandinavians already traded frequently in central Europe and across the North Sea.
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Close-up look at brain uptake of omega-3
Cryo-electron microscopy and computer simulations uncover how a cellular protein helps transport omega-3 fatty acids to the brain and eye, with implications for drug development.
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Vortex, the key to information processing capability: Virtual physical reservoir computing
By virtually reproducing physical reservoir computing, a new information processing technology, using numerical simulation, the present study reveals that vortices in fluid flow phenomena in the downstream region of a cylinder are the key to information processing capability. It is expected that this result concerning fluid flow vortices and information processing capability will be useful in enhancing the information processing capability of the physical reservoir using fluid flow.
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Passing the COVID test in just five minutes
Osaka University researchers create an intelligent nanopore system sensitive enough to detect single SARS-CoV-2 virus particles. By training a machine-learning algorithm, the platform was able to identify between various coronaviruses in just five minutes. This work may lead to fast and accurate point-of-care testing for COVID and other communicable diseases.
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After the big storm: How to supply emergency power
As demand for electricity rises and climate change brings more frequent and extreme storms, residents in rural and suburban communities must have access to the minimal electricity they need to survive a large, long-duration (LLD) power outage.
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Mutant genes can promote genetic transfer across taxonomic kingdoms
Researchers from Hiroshima University now have a better understanding of the mechanism underlying how certain bacteria can transfer genetic material across taxonomic kingdoms, including to fungi and protists. Their work, published in Frontiers in Microbiology, could have applications in changing how bacteria perform certain functions or react to changes in their environment.
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First report of dorsal navigation in a flying insect
Sweat bees navigate through dark tropical forests guided by canopy patterns.
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