A so-called 'jumping gene' that researchers long considered either genetic junk or a pernicious parasite is actually a critical regulator of the first stages of embryonic development, according to a new study in mice led by UC San Francisco scientists and published June 21, 2018 in Cell.
A major international study led by researchers from Lund University in Sweden has proven for the first time that certain nocturnally migrating insects can explore and navigate using the Earth's magnetic field. Until now, the ability to steer flight using an internal magnetic compass was only known in nocturnally migrating birds.
A zebrafish view of the world has been forensically analysed by researchers at the University of Sussex to reveal that how they see their surroundings changes hugely depending on what direction they are looking.
When cells grow and divide to ensure a biological function, DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins. When this process goes awry, the result could be diseases such as cancers. University of North Carolina School of Medicine researchers have discovered that a protein called Spt6 facilitates RNA degradation so that cells have just the right amount of RNA for the creation of proteins.
Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence linking viruses to Alzheimer's clinical traits and genetic factors. Researchers funded by the National Institute on Aging (NIA), part of the National Institutes of Health, made the discovery by harnessing data from brain banks and cohort studies participating in the Accelerating Medicines Partnership-Alzheimer's Disease (AMP-AD) consortium.
A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy. Paradoxically, the sending cells in this signaling are glioblastoma cells undergoing programmed cell death. The apoptotic cancer cells release extracellular vesicles. These vesicle, or exosomes, carry components that alter RNA splicing in the recipient glioblastoma cells, and this altered splicing promotes therapy resistance and aggressive migration.
A new study finds that mTORC1 controls how 'crowded' human cells become as a person ages.
Higher body mass index (BMI), especially in early adulthood, may be associated with reduced risk for premenopausal breast cancer.
African weakly electric fish, commonly called baby whales, use incredibly brief electrical pulses to sense the world around them and communicate with other members of their species. Part of that electrical mechanism exists in humans -- and by studying these fish, scientists may unlock clues about conditions like epilepsy.
Michigan Medicine researchers discover that stimulating the prefrontal cortex can induce wake-like behavior in anesthetized rats.
A first-of-its kind study, next generation sequencing is brought to bear to investigate a culprit in the path to Alzheimer's disease: the presence of viruses in the brain.
In a large-scale analysis published in the journal Neuron, researchers use data from three different brain banks to suggest that human herpesviruses are more abundant in the brains of Alzheimer's patients and may play a role in regulatory genetic networks that are believed to lead to the disease. This work lends support to the controversial hypothesis that viruses are involved in Alzheimer's disease and offers potential new paths for treatment.
Humans have unexpectedly high genetic variation in the receptor for a key pregnancy-maintaining hormone, according to research led by scientists at the Stanford University School of Medicine. The finding may help explain why some populations of pregnant women have an elevated risk of premature birth.
Researchers reporting in Current Biology on June 21 have found that nocturnal Bogong moths, like migratory birds, depend on the Earth's magnetic field to guide them on their way. The discovery offers the first reliable evidence that nocturnal insects can use the Earth's magnetic field to steer flight during migration, the researchers say.
Two strains of human herpesvirus -- human herpesvirus 6A (HHV-6A) and human herpesvirus 7 (HHV-7) -- are found in the brains of people with Alzheimer's disease at levels up to twice as high as in those without Alzheimer's, researchers from the Icahn School of Medicine at Mount Sinai report.
A remarkably high diversity of goblin spiders is reported from the Sri Lankan forests by two researchers from the National Institute of Fundamental Studies, Kandy, Sri Lanka. Nine new species are described in a recent paper in the open-access journal Evolutionary Systematics, where six are named after goblins and brownies from Enid Blyton's children's books. There are now 45 goblin spider species belonging to 13 genera known to inhabit the island country.
The World Desertification Atlas by the European Commission's Joint Research Centre provides the first comprehensive, evidence-based assessment of land degradation at a global level and highlights the urgency to adopt corrective measures.
A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. This is the first such synthetic enzyme to outperform its natural counterpart -- and it does so by three orders of magnitude.
Taking a walk may be a good opportunity to mentally review your to-do list, but using the time to instead be more mindful of your breathing and surroundings may help boost your wellbeing, according to researchers who found that while students reported being less stressed while they were on their feet and moving, they received an even greater benefit when they reported also being more mindful.
A year of schooling leaves students with new knowledge, and it also equates with a small but noticeable increase to students' IQ, according to a systematic meta-analysis published in Psychological Science, a journal of the Association for Psychological Science.