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Hepatitis C drugs boost Remdesivir's antiviral activity against COVID-19

Eurekalert - Apr 27 2021 - 00:04
Drugs used to treat hepatitis C render remdesivir 10 times better at inhibiting the SARS-CoV-2 coronavirus in cell cultures, according to a new study in Cell Reports.
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New approaches for teaching science remotely arise from the COVID-19 crisis

Eurekalert - Apr 27 2021 - 00:04
A new paper on college science classes taught remotely points to teaching methods that enhance student communication and collaboration, offering a framework for enriching online instruction as the coronavirus pandemic continues to limit in-person courses.
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Climate crises in Mesopotamia prompted the first stable forms of State

Eurekalert - Apr 27 2021 - 00:04
In the medium and long-term periods, climate shocks favoured cooperation among diverse groups of people. Indeed, by enlarging access to political and property rights, elites who had decision-making powers could work with other groups who held the skills and tools to overcome those crises
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The factors that improve job resiliency in North American cities have been identified

Eurekalert - Apr 27 2021 - 00:04
"Job connectivity" (the possibility of finding a similar job) is a key factor for the recovery of local economies in the face of crises, according to a study published recently in Nature Communications by researchers from the Universidad Carlos III de Madrid (UC3M), the Massachusetts Institute of Technology (MIT), the Max Planck Society and the University of Pittsburgh.
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New chemical tool that sheds light on how proteins recognise and interact with each other

Eurekalert - Apr 27 2021 - 00:04
A research group led by Professor Xiang David LI from the Department of Chemistry, The University of Hong Kong, has developed a novel chemical tool for elucidating protein interaction networks in cells. This tool not only facilitates the identification of a protein's interacting partners in the complex cellular context, but also simultaneously allows the 'visualisation' of these protein-protein interactions. The findings were recently published in the prestigious scientific journal Molecular Cell.
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Astronomers detect first ever hydroxyl molecule signature in an exoplanet atmosphere

Eurekalert - Apr 27 2021 - 00:04
An international collaboration of astronomers has detected a new chemical signature in the atmosphere of an extrasolar planet (a planet that orbits a star other than our Sun). The hydroxyl radical (OH) was found on the dayside of the exoplanet WASP-33b -- a so-called 'ultra-hot Jupiter', a gas-giant planet orbiting its host star much closer than Mercury orbits the Sun and therefore reaching atmospheric temperatures of more than 2,500° C.
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A new treatment that might keep COVID-19 patients off the ventilator

Eurekalert - Apr 27 2021 - 00:04
A new treatment is among the first known to reduce the severity of acute respiratory distress syndrome caused by the flu in animals, according to a new study.
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NUS researchers discover protein that promotes chemotherapy resistance

Eurekalert - Apr 27 2021 - 00:04
Researchers from NUS Medicine's Immunology Translational Research Programme and NUS Center for Cancer Research (N2CR) have identified how a molecule called DUSP16 plays an important role in a cancer patient's response to chemotherapeutic drugs. The study also found that chemotherapy drugs are a factor in the increased expression of DUSP16. This means that once chemotherapy begins, the expression of DUSP16 will increase in patients.
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Discerning molecular interactions may be target of precision medicine for severe COVID-19

Eurekalert - Apr 27 2021 - 00:04
lncRNAs are potential regulators of anti-viral response during severe SARS-CoV-2 infection. Researchers constructed a gene co-expression network that measures the relationship of gene expression patterns across a group of samples. They identified four differentially expressed lncRNAs strongly correlated to the protein-coding genes in a novel network enriched for different immune-related processes associated with dysregulated cytokine production. The four were identified as "hubs", signifying their association with cytokine over-production due to fierce immune response.
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Exercise reduces risk of airway disease

Eurekalert - Apr 27 2021 - 00:04
Exercise appears to reduce the long-term risk of bronchiectasis, a potentially serious disease of the airways, according to a new study.
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Linguists predict unknown words using language comparison

Eurekalert - Apr 27 2021 - 00:04
Researchers from SOAS University of London and the Max Planck Institute for the Science of Human History have published a new paper in the renowned international journal for historical linguistics, Diachronica. Their paper describes an experiment that illustrates how the classical method for the reconstruction of unattested languages can also be used to predict hitherto undocumented words in poorly described and endangered languages of India.
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Men's loneliness linked to an increased risk of cancer

Eurekalert - Apr 27 2021 - 00:04
A recent study by the University of Eastern Finland shows that loneliness among middle-aged men is associated with an increased risk of cancer.
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Limited value of tree plantations for biodiversity conservation

Eurekalert - Apr 27 2021 - 00:04
Tree plantations are supposed to help compensate the loss of pristine forest habitats. However, their contribution to biodiversity conservation is limited: For example, plantations host a significantly lower number of beetle species as well as individuals than old-growth forests. This was found by a global analysis published in Forest Ecology and Management and led by the German Centre for Integrative Biodiversity Research (iDiv), Friedrich Schiller University Jena (FSU) and Martin Luther University Halle-Wittenberg (MLU).
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The first comprehensive single-cell atlas of human teeth

Eurekalert - Apr 27 2021 - 00:04
Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.
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Life in a wheatbelt oasis

Eurekalert - Apr 27 2021 - 00:04
Western Australia's wheatbelt is a biodiversity desert, but the remaining wildlife - surviving in 'wheatbelt oases' - may offer insights for better conservation everywhere, according to researchers.
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Breakthrough in the understanding of a protein with a key role in several cancers

Eurekalert - Apr 27 2021 - 00:04
The neutron reflexometry method has given scientists an atomic-level insight into the behaviour of Bcl-2, a protein that promotes cancerous cell growth. The new study was carried out by Umeå chemists in collaboration with the research facilities ESS and ISIS and is published in Nature Communications Biology.
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The new EU climate target could phase out coal power in Europe as early as 2030

Eurekalert - Apr 27 2021 - 00:04
Tightening the EU emissions trading system (EU ETS) in line with the EU Green Deal would dramatically speed up the decarbonization of Europe's power sector - and likely cause a demise of the coal industry.
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Scientists created technology to detect and treat complex arrhythmias

Eurekalert - Apr 27 2021 - 00:04
Researchers have developed a breakthrough method for quickly, accurately, and reliably diagnosing cardiac arrhythmias. It coped with the task in 38 cases out of 51. In other words, it is highly effective in almost 75% of cases.
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International research team discovers new two-dimensional material

Eurekalert - Apr 27 2021 - 00:04
An international team with researchers from the University of Bayreuth has succeeded for the first time in discovering a previously unknown two-dimensional material by using modern high-pressure technology. The new material, beryllonitrene, consists of regularly arranged nitrogen and beryllium atoms. It has an unusual electronic lattice structure that shows great potential for applications in quantum technology.
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New clues on how networks such as Twitter are organized to respond to viral news

Eurekalert - Apr 27 2021 - 00:04
A thesis defended at the UOC analyses the structural patterns of complex systems such as social networks
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