Current therapies for Parkinson's disease are mainly of a replacement type and pose problems in the long term, so the challenge is to establish an early diagnosis and develop neuroprotective and neurorestorative therapies that will allow the symptoms of the disease to be slowed down or even reversed. As part of her PhD thesis, Catalina Requejo, documented the regenerative, neuroprotective effect of two neurotrophic factors when they are applied in a combined way.
Researchers at Linköping University in Sweden have discovered a previously unknown warning system that contributes to the body's immune system. Mitochondria in the white blood cells secrete a web of DNA fibers that raises the alarm. The results have been published in the scientific journal PNAS, and may lead to increased knowledge about autoinflammatory diseases and cancer.
A group of Michigan State University researchers specializing in quantum calculations has proposed a radically new computational approach to solving the complex many-particle Schrödinger equation, which holds the key to explaining the motion of electrons in atoms and molecules.
University of Cincinnati biologist Bruce Jayne studied the mechanics of snake movement to understand exactly how they can propel themselves forward like a train through a tunnel. His study titled 'Crawling without Wiggling' was published in the Journal of Experimental Biology.
The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades.
Extended shift work has historically been linked to interrupted sleep patterns and risk of injury, and is a persistent problem for emergency medical services (EMS) personnel who are tasked with delivering acute care under significant pressure. New guidelines, written by a team led by University of Pittsburgh School of Medicine scientists aim to mitigate the effects of fatigue by addressing the impact of shift work and scheduling.
It is well known that healthy eating increases our general sense of wellbeing. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now discovered that a fiber-rich diet can have a positive influence on chronic inflammatory joint diseases, leading to stronger bones.
Global warming affects more than just plant biodiversity -- it even alters the way plants grow. A team of researchers at Martin Luther University Halle-Wittenberg (MLU) joined forces with the Leibniz Institute for Plant Biochemistry (IPB) to discover which molecular processes are involved in plant growth. In the current edition of the internationally renowned journal "Current Biology", the group presents its latest findings on the mechanism controlling growth at high temperatures.
A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.
New epidemiological study finds no connection between cases of cancer and use of plant protection products containing glyphosate
BfR Communication No. 036/2017 from 22 December 2017Epidemiological studies are a central element of public discussion in the debate surrounding the carcinogenic potential of glyphosate. A publication that appeared in the USA in November examined whether there is a possible connection between the use of glyphosate containing plant protection products and cases of cancer among people who work in agriculture using a significantly broader data base.
The paper, titled "Collocated ionosonde and dense GPS/GLONASS network measurements of midlatitude MSTIDs", covers the first ever complex analysis of MSTIDs obtained by two methods of radio sounding. MSTIDs, which are huge wave perturbations somewhat resembling aurora borealis, are invisible in midlatitude areas.
Researchers have demonstrated the potential of a new class of drugs for the treatment of refractory chronic obstructive pulmonary disease, i.e. COPD. Incurable to date, the disease is one of the most frequent causes of death worldwide and is typically triggered by smoking. In the current preclinical study, two anti-inflammatory substances have proved more effective than preparations used to date. The results were published in the Journal of Allergy and Clinical Immunology.
A lot of research is being conducted into the acidification of the world's oceans. A recent study has proved that freshwater bodies are likewise affected. Rising carbon dioxide levels could upset the balance of species.
The fat of obese people becomes distressed, scarred and inflamed, which can make weight loss more difficult, research at the University of Exeter has found.
The digital reconstruction of the skull of a 200-million-year-old South African dinosaur, Massospondylus, has made it possible for researchers to make 3-D prints and in this way facilitate research on other dinosaurs all over the world.
The Joint Research Centre, the European Commission's science and knowledge service, provided expert input on the mapping of urban accessibility worldwide to support global and local decision-making on development and environmental policies.
The failure of SSRI antidepressants can be a result of genetic variations in patients. Variations within the gene that encodes the CYP2C19 enzyme results in extreme differences in the levels of escitalopram achieved in patients, according to a new study from Karolinska Institutet in Sweden and Diakonhjemmet Hospital in Norway published in The American Journal of Psychiatry. Prescribing the dose of escitalopram based on a patient's specific genetic constitution would greatly improve therapeutic outcomes.
In 2004, a tsunami devastated much of the Indonesian city of Banda Aceh. An international team of researchers has studied the long-term impact that rebuilding efforts in coastal areas have had on the community.
Environmental DNA analysis makes it possible to detect water organisms without having to capture them first. For the first time, a team at the Technical University of Munich (TUM) systematically investigated the effect of various environmental factors on environmental DNA analyses. By doing so, the researchers have made an important step towards the standardized application of this method for the monitoring of water bodies.
A new article lays the groundwork for alternative climate mitigation scenarios that place less reliance on unproven negative emissions technologies in the future.