Health care insurers including Medicare, Medicaid and major private insurers have not done enough to combat the opioid epidemic, suggests a study led by researchers at Johns Hopkins Bloomberg School of Public Health.
An analysis of prescription drug coverage policies for the treatment of low back pain suggests insurers could help to reduce opioid overuse by expanding access to opioid alternatives through coverage and reimbursement policies.
An analysis of Medicare claims data suggests chronic opioid use in US counties corresponded with support for Republican Donald Trump in the 2016 presidential election, with much of the correlation explained by socioeconomic factors.
Colorado State University polymer chemists have taken another step toward a future of high-performance, biorenewable, biodegradable plastics. Publishing in Nature Communications, the team led by Professor of Chemistry Eugene Chen describes chemical synthesis of a polymer called bacterial poly(3-hydroxybutyrate) - or P3HB. The compound shows early promise as a substitute for petroleum plastics in major industrial uses.
Art curators will be able to recover images on daguerreotypes, the earliest form of photography that used silver plates, after a team of scientists led by Western University learned how to use light to see through degradation that has occurred over time.
It's been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have discovered the secret to the gene's success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in today's online edition of Nature, offers a novel approach for attacking many disease-causing viruses.
Correlative light-electron microscopy is being used to increase our knowledge of how platelets are made in the body and the results are challenging previously held understandings.
Researchers at Nemours and the University of Delaware have developed a blood test predictive of spastic cerebral palsy. Their study, published in BMC Bioinformatics, showed that DNA patterns in circulating blood cells can be used to help identify spastic CP patients (Crowgey et al.). New and better ways to identify infants with CP are needed so that interventions can start earlier for more children.
A team of Lobachevsky University researchers led by Professor Zaretkhan Saralieva is exploring the potential of social services for the elderly by public and religious organizations of modern Russia. Their work is focused on the transformation of social work with the elderly during the last four years in the context of contractual relations in social services and participation of socially-oriented non-profit organizations in the competition for state subsidies.
To help prevent possible complications such as nonunion at large fracture sites, researchers have developed a cartilage matrix that mimics the early stages of repair and provides the essential structural and biological properties needed by bone-forming cells to divide and grow.
A new CAMH and Institute for Clinical Evaluative Sciences study shows that people with schizophrenia account for more than one in 10 cases of suicide in Ontario, and that young people are disproportionately affected.People with schizophrenia also had more contact with the health care system, pointing to an opportunity to intervene. The researchers emphasize the need for early suicide risk assessments to reduce risks.
In this work, guanidine cation CN3H6+ and 3-amino-1,2,4-triazole C2H4N4 were crystallized into NaN5 and two novel energetic coordination polymers (CPs), (NaN5)5[(CH6N3)N5](N5)3- and (NaN5)2(C2H4N4) were prepared respectively via a self-assembly process. The decomposition temperatures of both polymers increase to 118.4 and 126.5°C respectively. Moreover, no crystallized H2O was generated in products to afford the anhydrous compounds of pentazole salts as promising energetic materials.
Russian researchers together with their French colleagues discovered that a genuine feature of superconductors -- quantum Abrikosov vortices of supercurrent -- can also exist in an ordinary nonsuperconducting metal put into contact with a superconductor. The observation of these vortices provides direct evidence of induced quantum coherence. These fundamental results enable a better understanding and description of the processes occurring at the interface between superconducting and normal phases, which is important for future quantum technology.
In the photoelectric effect, a photon ejects an electron from a material. Researchers at ETH have now used attosecond laser pulses to measure the time evolution of this effect in molecules. From their results they can deduce the exact location of a photoionization event.
A new paper in Scientific Reports looks at how to extract cellular protein synthesis machinery from human blood, and, by adding recombinant DNA to the extract, to produce therapeutic proteins within two hours.
Origin Quantum Company cooperates with the team of Prof. Guang-Can Guo from the CAS Key Laboratory of Quantum Information, USTC (LQCC). They have performed a 64-qubit circuit simulation, and even revealed the possibility of a 72-qubit circuit simulation.
Understanding how the retina transforms images into signals that the brain can interpret would not only result in insights into brain computations, but could also be useful for medicine. As machine learning and artificial intelligence develop, eye diseases will soon be described in terms of the perturbations of computations performed by the retina. A newly developed model of the retina can predict with high precision the outcome of a defined perturbation.
Heart failure is almost as common in women as men, but its characteristics vary by sex. A new review summarizes the current state of sex-sensitive issues related to heart failure drugs included in treatment guidelines, and suggests future directions for improved care.
Combinations of cancer drugs can be quickly and cheaply tested on tumour cells using a novel device developed by EMBL scientists. The research, reported in Nature Communications on June 22, marks the latest advancement in the field of personalised medicine.
New research based on the Italian experience with outbreaks of Chikungunya, a disease borne by the tiger mosquito, in 2007 and 2017, shows that different vector control strategies are needed, depending on the time when the first cases are notified, 'thus providing useful indications supporting urgent decision-making of public health authorities in response to emerging mosquito-borne epidemics', Bocconi University's Alessia Melegaro says.