The pitter patter of little feet... climbing straight up a wall

The pitter patter of little feet... climbing straight up a wall

Building upon several years of research into the gecko's uncanny ability to climb sheer walls, researchers at the University of California, Berkeley, have developed an adhesive that is the first to master the easy attach and easy release of the reptile's padded feet. The material could prove useful for a range of products, from climbing equipment to medical devices.

Stem cell therapy studies for stroke, cerebral palsy prepare for clinical trials

Stem cell therapy studies for stroke, cerebral palsy prepare for clinical trials

Finding answers about optimal dosage and timing for stem cell therapy in adults with strokes and newborns with ischemic injuries is a goal of two new federally funded studies.

The answers are critical before clinical trials can begin, says Dr. Cesario V. Borlongan, neuroscientist at the Medical College of Georgia and Charlie Norwood Veterans Affairs Medical Center. He is principal investigator on the National Institutes of Health grants totaling $6 million that also will explore long-term benefits of cell therapy.

Secondhand smoke exposure is linked to worsening of lung function for persons with cystic fibrosis

Exposure to secondhand smoke is associated with adverse effects on lung function among persons with cystic fibrosis, with this effect being worse for persons with certain gene variations, according to a study in the January 30 issue of JAMA.

Common drug-releasing coronary stents appear to have similar clinical outcomes

A comparison of use of the first two commercially available drug-releasing coronary stents (for the medications sirolimus and paclitaxel) among patients in “everyday clinical practice” indicates no significant differences for outcomes such as heart attack or cardiac death, according to a study in the January 30 issue of JAMA.

Other highlights in the Jan. 29 JNCI

Protein Associated with Poor Breast Cancer Prognosis

High levels of the Ki-67 protein are associated with poor prognosis in early breast cancer patients, but it may not able to predict which patients will benefit from additional chemotherapy.

The percentage of proliferating cells in a tumor is a predictor of breast cancer prognosis. The level of Ki-67 expression is sometimes used as a measure of cell proliferation. Some studies have suggested that breast tumors with a high percentage of cells expressing Ki-67 are more responsive to chemotherapy.

Sex hormones unrelated to prostate cancer risk

Sex hormones circulating in the blood do not appear to be associated with prostate cancer risk, according to data from 18 prior studies. The analysis will be published online January 29 in the Journal of the National Cancer Institute.

Having high levels of male sex hormones, known as androgens, has long been hypothesized as a risk factor for prostate cancer. Nearly two dozen prospective studies have examined the relationship between circulating sex hormones and prostate cancer risk, but the results have been inconsistent.

Physician characteristics are associated with quality of cancer care

Whether a woman receives radiation after breast cancer surgery may be associated with certain characteristics of her surgeon, including sex and medical training, according to a study published online January 29 in the Journal of the National Cancer Institute.

Using DNA, scientists hunt for the roots of the modern potato

MADISON -More than 99 percent of all modern potato varieties planted today are the direct descendents of varieties that once grew in the lowlands of south-central Chile. How Chilean germplasm came to dominate the modern potato-which spread worldwide from Europe-has been the subject of a long, contentious debate among scientists.

Smithsonian study: Sediment prediction tools off the mark

A recent study led by Smithsonian ecologist Kathy Boomer suggests it is time for a change in at least one area of watershed management. Boomer has been examining the tools scientists and managers use to predict how much sediment runs into the Chesapeake Bay, and by her account, they are way off the mark. The study, co-authored by SERC ecological modeler Donald Weller and ecologist Thomas Jordan, appears in the January/February issue of the Journal of Environmental Quality.

With a jolt, 'nanonails' go from repellant to wettable

MADISON -- Sculpting a surface composed of tightly packed nanostructures that resemble tiny nails, University of Wisconsin-Madison engineers and their colleagues from Bell Laboratories have created a material that can repel almost any liquid.

Add a jolt of electricity, and the liquid on the surface slips past the heads of the nanonails and spreads out between their shanks, wetting the surface completely.