Nanotechnology innovation may revolutionize gene detection in a single cell

Nanotechnology innovation may revolutionize gene detection in a single cell

Scientists at Arizona State University’s Biodesign Institute have developed the world’s first gene detection platform made up entirely from self-assembled DNA nanostructures. The results, appearing in the January 11 issue of the journal Science, could have broad implications for gene chip technology and may also revolutionize the way in which gene expression is analyzed in a single cell.

UT Health Science Center researchers decoding saliva to detect breast cancer

UT Health Science Center researchers decoding saliva to detect breast cancer

HOUSTON – (Jan.10, 2008)—Researchers at The University of Texas Health Science Center at Houston can identify and quantify specific protein markers in human saliva to provide an early, non-invasive diagnosis of breast cancer, according to a study published in the Jan. 10, 2008 issue of the journal "Cancer Investigation."

The study describes how the onset of breast cancer produces a change in the normal type and amount of proteins in glandular secretions from the salivary glands. The protein profile in a healthy person is altered by the presence of cancer.

New picture of HIV-1's protein jacket identifies target for antibody-based vaccine

New picture of HIV-1's protein jacket identifies target for antibody-based vaccine

BOSTON--By coaxing the HIV-1 protein to reveal a hidden portion of its protein coat, scientists at Dana-Farber Cancer Institute and Harvard Medical School have provided a newly detailed picture of how protective, or so-called broadly neutralizing, antibodies block HIV-1 infection.

UCLA scientists identify new genetic link to autism

UCLA scientists have used language onset – the age when a child speaks his first word – as a tool for identifying a new gene linked to autism. The team also discovered that the gene is most active in brain regions involved with language and thought. Interestingly, evidence for the genetic link came from the DNA of families with autistic boys, not those with autistic girls.

Evidence of glaciation in 'super greenhouse' world

Large ice-sheets existed on Earth about 91 million years ago, during one of the warmest periods since life began, an international team of scientists reports this week.

The findings, published in the journal 'Science', challenges the popular assumption that large glaciers could not have existed in the 'super greenhouse' climate, when tropical surface ocean temperatures reached as high as 35-37C (95-98.6F) and alligators lived in the Arctic.

Africa's biggest mammals key to ant-plant teamwork

GAINESVILLE, Fla. --- Throughout the tropics, ants and Acacia trees live together in intricate interdependent relationships that have long fascinated scientists.

Now researchers are reporting that in Africa, this plant-insect teamwork depends on the very antagonist it is intended to ward off: Africa’s big browsing mammals.

Genomic screen nets hundreds of human proteins exploited by HIV

BOSTON, Mass. (Jan. 10, 2008) — In some ways, HIV resembles a minimalist painter, using a few basic components to achieve dramatic effects. The virus contains just nine genes encoding 15 proteins, which wreak havoc on the human immune system. But this bare bones approach could have a fatal flaw. Lacking robust machinery, HIV hijacks human proteins to propagate, and these might represent powerful therapeutic targets.

Teens getting help for suicidal behavior from an online community

It’s a topic people often don’t want to talk about, but suicide is a serious issue that needs serious attention.

According to a University of Alberta researcher, teens are difficult to reach and there have traditionally been few services that directly target adolescent suicidal behavior. Elaine Greidanus says many teens aren’t picking up a phone, or seeing a counsellor, they’re more likely logging on for emotional support.

Greidanus, a grad student in Educational Psychology, did a study to see how helpful cyber support really is.

Doctor 'pay-for-performance' improves patient care

Los Angeles, Calif. – January 10, 2008 - A new study examines whether patients seeing physicians participating in a “pay-for-performance” incentive program receive better care than those who saw non-participating physicians. The health plan that was examined reimburses physicians based on the quality of care they provide.

Researchers shed light on genetic factors behind UK's biggest killer