Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway

PHILADELPHIA – Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer’s disease.

Researchers reveal HIV peptide's possible pathway into the cell

Researchers reveal HIV peptide's possible pathway into the cell

Troy, N.Y. - Two theoretical physicists at Rensselaer Polytechnic Institute have uncovered what they believe is the long-sought-after pathway that an HIV peptide takes to enter healthy cells. The theorists analyzed two years of biocomputation and simulation to uncover a surprisingly simple mechanism describing how this protein fragment penetrates the cell membrane. The discovery could help scientists treat other human illnesses by exploiting the same molecules that make HIV so deadly proficient.

Scratching an itch: Neutralizing IL-22 prevents psoriasis in mice

Engineered mice provide insight into Alzheimer's disease

Discovery opens door to 'personalized' asthma therapy

GALVESTON, Texas — In the last few years, “personalized medicine”— using genetic or other molecular biology-based diagnostic tests to customize treatment for a particular patient — has emerged as a powerful new tool for health care.

Therapy guided by genetic testing has proven highly successful in treating some types of leukemia and breast and lung cancer. Similar “personalized” therapies are on the horizon for other types of cancer, as well as diabetes, heart disease and other deadly disorders.

Study finds significant differences in protocols hospitals use to determine brain death

A survey of some of the top hospitals in the country has found that protocols followed to determine brain death differ significantly among those institutions. In the January 22 issue of the journal Neurology, a team of researchers reports finding that brain death protocols at hospitals cited as top neurology and neurosurgery centers by U.S. News and World Report often do not follow the standards established by the American Academy of Neurology (AAN). The paper has received early online release.

New way to produce high-vitamin corn could improve nutrition in developing countries

Scientists have developed a potentially powerful new tool in the fight against deficiencies in dietary vitamin A, which cause eye diseases, including blindness, in 40 million children annually, and increased health risks for about 250 million people, mostly in developing countries.

Oak Ridge leads DOE INCITE effort in 2008

OAK RIDGE, Tenn., Jan. 17, 2008 – Scientific studies on climate change, energy and alternative fuels are among the 30 projects awarded more than 145 million processing hours on supercomputers at Oak Ridge National Laboratory through the Department of Energy’s Innovative and Novel Computational Impact on Theory and Experiment (INCITE) program.

Rapid effects of intensive therapy seen in brains of patients with OCD

Report identifies research to bolster knowledge of health effects of wireless communication devices

WASHINGTON -- The rapid increase in the use of wireless communication devices in recent years has been accompanied by a significant amount of research into potential health effects from high exposure to radiofrequency (RF) energy emitted by these devices. A new National Research Council report, requested by the U.S. Food and Drug Administration, identifies research that could further extend understanding of long-term low exposure to these devices.